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Project Ideas for Biochemistry and Molecular Biophysics Students

Delve into protein structure, enzymology, and structural biology at Caltech through advanced biochemistry and molecular biophysics research.

🔬 Introduction

Caltech’s MS in Biochemistry and Molecular Biophysics prepares students for cutting-edge research in protein science, molecular design, and biological systems. The program integrates advanced lab techniques with molecular simulation and data-driven biophysics.

📘 Suggested Thesis Topics

Molecular Dynamics Simulations of Protein Folding Mechanisms

Structure-Based Drug Design Targeting Viral Enzymes

NMR Spectroscopy to Study Protein-Ligand Interactions

Real-Time Fluorescence Analysis of Enzyme Kinetics

Cryo-EM Reconstruction of Membrane Protein Complexes

Mutagenesis and Functional Analysis of Kinase Enzymes

Biophysical Characterization of Intrinsically Disordered Proteins

Computational Docking of Small Molecules to Protein Active Sites

Design and Evolution of Artificial Enzymes

Understanding Protein Aggregation in Neurodegenerative Diseases

Structural Analysis of Riboswitches and Their Regulatory Functions

Kinetic Modeling of Allosteric Regulation in Metabolic Pathways

Quantitative Study of Molecular Transport in Cells

Exploring Redox Biology Through Fluorescent Biosensors

Atomic Force Microscopy in Protein Surface Interaction Studies

Collexa – Biophysics & Biochemistry Support

Collexa helps Caltech students excel in structural biology and molecular biophysics with access to mentorship, data interpretation, and project guidance tools.

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