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Dissertation Topics for Ph.D. in Biology

Pursue fundamental biological discoveries and applied innovation with these advanced Ph.D. research ideas in genetics, systems biology, and neuroscience.

🧬 Introduction

Princeton’s Ph.D. in Biology trains researchers to make breakthrough contributions across molecular biology, neurobiology, and ecological systems. These dissertation topics reflect the intersection of experimental rigor and computational modeling in modern biological science.

🔬 Suggested Dissertation & Research Topics

CRISPR-Cas9 Applications in Functional Genomics of Developmental Genes

Neural Circuit Mapping of Social Behavior in Model Organisms

Epigenetic Regulation of Stem Cell Differentiation in Mammals

Synthetic Gene Networks for Environmental Biosensing

Comparative Transcriptomics in Adaptive Evolution of Extremophiles

Molecular Mechanisms of Mitochondrial Quality Control

Signal Transduction Pathways in Tumor Microenvironments

Biomechanics of Morphogenesis in Vertebrate Embryos

Host-Microbiome Interactions in Gut-Brain Axis Regulation

Gene Regulatory Networks in Embryonic Pattern Formation

Real-Time Imaging of Calcium Dynamics in Neurons

Adaptive Immunity and B-Cell Repertoire Diversity Analysis

Mechanistic Studies of Protein Folding and Misfolding Diseases

Functional Role of Long Non-Coding RNAs in Brain Development

Evolutionary Tradeoffs in Metabolic Pathways of Insects

Organoid Models for Disease Modeling and Drug Discovery

Mathematical Modeling of Gene Expression Noise

Photoreceptor Cell Regeneration Using Optogenetics

Population Genomics of Migratory Birds in Changing Climates

Genetic and Epigenetic Mechanisms of Lifespan Extension

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