Princeton’s Ph.D. in Molecular Biology trains scholars to explore cellular and molecular processes at the heart of biology and medicine. The following dissertation topics cover advanced research in genomics, gene regulation, molecular diagnostics, and therapeutic innovation.
CRISPR-Cas Systems for Precision Gene Editing in Stem Cells
Molecular Mechanisms of RNA Interference in Cancer Suppression
Regulation of Cell Cycle Checkpoints in Tumor Progression
Transcriptional Reprogramming in Cellular Senescence
Epigenetic Landscape Shifts in Neurodegenerative Disorders
Protein-Protein Interactions in DNA Repair Pathways
Mechanosensation and Signal Transduction in Cell Adhesion
Gene Regulatory Networks in Embryonic Development
Targeting Oncogenes with Synthetic Lethality Approaches
Long Non-Coding RNAs in Immune Cell Differentiation
Metabolic Rewiring in Hypoxia-Driven Cellular Adaptation
Single-Cell Transcriptomics for Tumor Microenvironment Mapping
Structural Biology of Viral Replication Complexes
miRNA Biogenesis Pathways in Developmental Disorders
Synthetic Biology Circuits for Therapeutic Protein Expression
Pathogen-Host Interactions in Intracellular Bacterial Infections
DNA Methylation Patterns in Autoimmune Disease Onset
Endoplasmic Reticulum Stress and Apoptotic Signaling Cascades
Chaperone-Mediated Protein Folding in Neurodegeneration
Translational Control in mRNA Surveillance Pathways
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