The University of Chicago’s Ph.D. in Biological Sciences offers interdisciplinary training in cutting-edge life science fields. These dissertation topics help students explore the mechanisms of life from molecules to systems, leveraging both lab and computational expertise.
CRISPR-Based Gene Editing Strategies for Rare Genetic Disorders
Single-Cell Transcriptomics to Map Immune Cell Differentiation
The Role of Microbiome Diversity in Inflammatory Bowel Diseases
Neurogenesis and Synaptic Plasticity in Aging Brains
3D Organoid Models for Studying Pancreatic Cancer Progression
Epigenetic Regulation of Stem Cell Fate Decisions
Computational Modeling of Cell Signaling Pathways in Cancer
RNA-Binding Proteins and Post-Transcriptional Gene Regulation
Mechanisms of Antigen Presentation in Adaptive Immunity
Bioinformatics Pipeline for Predicting Protein–Protein Interactions
Molecular Mechanisms Underlying Circadian Rhythm Disorders
Role of Long Non-Coding RNAs in Neuronal Development
High-Resolution Imaging of Cellular Organelles Using Cryo-EM
Synthetic Biology Approaches to Engineering Metabolic Pathways
Genome-Wide Association Studies (GWAS) for Autoimmune Diseases
Machine Learning in Drug Discovery for Neurodegenerative Diseases
Developmental Genetics of Vertebrate Limb Formation
Immune Checkpoint Regulation in Tumor Microenvironments
Live-Cell Imaging of Mitochondrial Dynamics and Apoptosis
Comparative Genomics for Evolutionary Insights in Model Organisms
Regenerative Biology: Mechanisms of Tissue Repair in Zebrafish
Multi-Omics Integration for Personalized Cancer Therapy
Cellular Senescence and Its Role in Age-Related Pathologies
Synthetic Gene Circuits for Cell Fate Programming
Functional Genomics Using CRISPR Screens in Disease Models
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