The PhD program in Biochemistry, Biophysics, and Chemical Biology at the University of Pennsylvania focuses on the molecular mechanisms underlying health and disease. The following dissertation topics highlight key areas in protein structure, molecular biology, and drug discovery.
Structural Biology: Understanding Protein Folding and Misfolding
Molecular Mechanisms of Disease: From Cancer to Neurodegeneration
Drug Discovery and Development in Cancer Therapy
Computational Biophysics: Modeling Protein-Ligand Interactions
Molecular Mechanisms in Cellular Signaling Pathways
Protein Engineering for Biotechnological Applications
The Role of Chaperones in Protein Folding and Stability
Metabolomics: Understanding Cellular Metabolic Networks
Development of Targeted Nanomedicines for Drug Delivery
Biophysical Techniques for Studying Protein Dynamics
Mechanisms of Drug Resistance in Bacterial and Viral Infections
Designing Inhibitors for Targeting Protein-Protein Interactions
Mechanisms of DNA Repair in Cancer Cells
The Role of Lipid Membranes in Cellular Function and Disease
Single-Cell Genomics: Unraveling Cellular Heterogeneity
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