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Project Ideas for Doctor of Philosophy in Quantitative Biosciences

Decode living systems with mathematics, physics, and high-density data.

🏛 Introduction

Georgia Tech’s QBioS PhD arms biologists with stochastic-process toolkits and GPU clusters. Cohorts model viral dynamics in single cells, visualize developmental genetics in light-sheet microscopes, and mine terabytes of microbiome metagenomes. Rotations range from CRISPR lineage tracing in zebrafish embryos to agent-based tumor eco-evolution, producing alumni who publish in Cell and debug CUDA kernels with equal ease.

💡 Suggested Project Titles

Agent-based model of tumor–immune eco-evolutionary dynamics

Bayesian inference of ribosome-profiling translation rates

Topology-guided analysis of protein-folding energy landscapes

CRISPR lineage-tracing reconstruction algorithms in zebrafish

Neural-ODE surrogate for intracellular viral replication cycles

Single-cell multi-omic integration via graph variational auto-encoders

Biome-scale metagenomic assembly of coastal nitrogen cycling

Optogenetic control of synthetic toggle-switch circuits in yeast

Stochastic modeling of antibiotic persistence in biofilms

Phase-field simulation of bacterial colony pattern formation

Evolutionary game theory of microbiome metabolic cross-feeding

Deep-learning enhancer-promoter interaction predictor

Kinetic Monte-Carlo of actin network polymerization forces

Spatial transcriptomics data-viz pipeline for brain slices

Techno-economic analysis of cell-free biomanufacturing platforms

Georgia Tech – PhD in Quantitative Biosciences

Marry theory and data to reveal life’s hidden algorithms.

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