NYU’s PhD in Biochemistry trains scientists to explore the molecular machinery of life, focusing on protein structure, enzymatic pathways, gene regulation, and cellular signaling. With access to world-class labs, students apply techniques in X-ray crystallography, NMR, CRISPR, and mass spectrometry. The program emphasizes translational research in cancer, neurodegeneration, and immunology. Graduates lead in academia, biotech, and pharmaceutical innovation.
Structural analysis of kinase inhibitors binding to mutated cancer signaling proteins via cryo-EM techniques
Investigating post-translational modifications in Alzheimer’s disease-related tau aggregation pathways
CRISPR-based gene knockdown for metabolic pathway dissection in mitochondrial dysfunction disorders
Studying ribosomal stalling mechanisms using nascent chain profiling and ribosome footprinting
Mechanistic investigation of DNA repair enzymes using mutational scanning and kinetic assays
Designing allosteric inhibitors targeting HIV reverse transcriptase for drug-resistance suppression
Isotopic labeling of peptides for real-time proteasome degradation monitoring
High-throughput screening of small molecules affecting unfolded protein response in ER stress conditions
ATPase activity regulation in molecular chaperones involved in protein folding diseases
Quantifying coenzyme utilization in bacterial vs. eukaryotic metabolic enzymes under stress
Lipid–protein interaction studies using surface plasmon resonance and fluorescent lipid analogs
Comparing antioxidant enzymatic activity in age-related tissue degeneration across species
Structural elucidation of multi-subunit protein complexes involved in immune signaling
Single-molecule FRET to analyze enzyme conformational changes during catalysis
Investigating chromatin remodeling enzymes using site-directed mutagenesis
Kinetic modeling of glycolytic flux under hypoxic conditions in tumor microenvironments
RNA-binding protein mapping via CLIP-seq in neuronal differentiation
Analysis of proteolytic processing in apoptotic cell death pathways
Studying coenzyme Q biosynthesis enzymes for targeted mitochondrial therapy
Engineering riboswitches for synthetic biology applications in drug-sensing biosensors
Advance biomedical research at the molecular level in NYU’s cutting-edge Biochemistry PhD.
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