UC’s MS in Chemical Biology merges chemistry and life sciences to design probes, drugs, and biomolecular technologies addressing health and sustainability.
Click-chemistry probes mapping protein-protein interactions in live neurons
Photoactivatable kinase inhibitor studying signaling-pathway dynamics
CRISPR-compatible base-editor chemical enhancement improving specificity
Metabolite-responsive fluorescent sensor imaging cancer cell metabolism
Synthetic glycoconjugate vaccine targeting antibiotic-resistant bacteria
Peptidomimetic inhibitor disrupting SARS-CoV-2 main protease
Biorthogonal cleavage tag enabling temporal control of protein degradation
High-throughput screen of marine natural products against Alzheimer tau aggregation
Supramolecular cage delivering siRNA across the blood–brain barrier
NMR study of intrinsically disordered region conformations upon ligand binding
PROTAC library design targeting oncogenic transcription factors
Chemoenzymatic synthesis of novel nucleoside analogues for antiviral therapy
Microbial pathway engineering producing biodegradable plastics precursors
Covalent fragment library mapping cysteine hotspots in epigenetic enzymes
Single-cell mass-spec imaging of lipid heterogeneity in tumor microenvironments
Ethics paper on dual-use concerns in synthetic biosynthetic pathways
Machine-learning model predicting off-target reactivity of electrophilic warheads
Outreach kit demonstrating fluorescence sensors in secondary-school labs
Conference poster on chemical-genetic control of plant drought tolerance
Review article on advances in activity-based protein profiling
Probe life’s chemistry and create novel therapeutics with UC’s cutting-edge MS.
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