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Project Ideas for Doctor of Philosophy in Chemical Biology

Molecular tools to probe and reprogram living systems.

🏛 Introduction

UC’s PhD in Chemical Biology merges chemistry with life science to design probes, drugs, and biomolecular technologies addressing health and sustainability challenges.

💡 Suggested Project Titles

Click-chemistry probes mapping protein-protein interactions in neurons

Photoactivatable kinase inhibitor studying signaling dynamics

Covalent fragment library targeting cysteine hotspots in epigenetic enzymes

Metabolite-responsive fluorescent sensor imaging cancer metabolism

Peptidomimetic inhibitor disrupting SARS-CoV-2 main protease

Supramolecular cage delivering siRNA across the blood–brain barrier

Activity-based protein profiling of antibiotic resistance pathways

Microbial pathway engineering producing biodegradable plastics monomers

Proteomics of lipid heterogeneity in tumor microenvironments

White paper on dual-use risks in synthetic biosynthetic routes

University of California – PhD in Chemical Biology

Probe life’s chemistry with UC’s molecule-centric PhD.

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