The PhD in Microbiology, Immunology, and Cancer Biology (MIC) at UVA immerses students in high-impact research that bridges infection biology, immune system regulation, and cancer mechanisms. With strong NIH support and translational collaborations, students delve into the molecular basis of host-pathogen interactions, tumor immunology, and vaccine development. This program emphasizes experimental rigor, interdisciplinary methods, and real-world clinical applications, preparing students for roles in academic medicine, pharma, and biotech.
Immunomodulatory effects of checkpoint inhibitors in solid tumors
Microbial metabolite influence on gut immune homeostasis
CRISPR screens for host factors in viral replication
T-cell receptor diversity mapping in autoimmune disease models
Bacterial biofilm resistance mechanisms and antibiotic development
Tumor microenvironment profiling using single-cell RNA-seq
Comparative vaccine design using mRNA vs. viral vectors
Cytokine storm dynamics in sepsis and ARDS
Innate immune evasion strategies in intracellular pathogens
Analysis of tumor-associated macrophage polarization
Therapeutic modulation of the gut-lung axis in infection
Targeting PD-L1 expression pathways in resistant cancers
Cross-talk between dendritic cells and NK cells in tumor surveillance
Host-pathogen protein interaction networks
Viral latency regulation in herpesvirus infections
Adaptive immune memory in mucosal infections
Epigenetic regulation in oncogenic virus-infected cells
Engineering bacterial vectors for targeted cancer therapy
Investigate immunity, infection, and oncogenesis with UVA’s interdisciplinary PhD in Microbiology, Immunology, and Cancer Biology.
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