UVA’s PhD in Molecular Physiology and Biological Physics provides rigorous training at the interface of molecular biology, physical sciences, and systems physiology. Students tackle research questions involving ion channel regulation, cardiac function, neural signaling, and bioenergetics. The program promotes technical mastery in electrophysiology, structural biology, and computational modeling, enabling translational discoveries that bridge basic science with clinical impact.
Electrophysiological study of sodium channelopathies in cardiac tissue
Cryo-EM of ion channels under mechanical stress
Calcium signaling regulation in muscle contraction
3D modeling of neurotransmitter receptor conformational states
Molecular basis of insulin resistance in skeletal muscle
Metabolic flux analysis in mitochondrial dysfunction
Single-channel patch clamp analysis in neuron cultures
ATP-sensitive potassium channel regulation in ischemia
Computational fluid dynamics of blood flow in microvasculature
Photonic biosensors for monitoring pH in live tissues
Investigating baroreceptor sensitivity in hypertension models
Voltage-clamp fluorometry for real-time protein conformational changes
Redox regulation of metabolic enzymes in the heart
Signal transduction modeling in hormonal pathways
Comparative physiology of cold adaptation in mammals
Biophysical basis of pain receptor desensitization
Multi-scale modeling of pulmonary function in disease states
Ion channel drug binding dynamics for cardiac arrhythmia therapy
Bridge molecular biology and biophysics to understand disease with UVA’s PhD in Molecular Physiology and Biological Physics.
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