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Project Ideas for Doctor of Philosophy in Biological Sciences

Interdisciplinary exploration of life-processes from molecules to ecosystems.

🏛 Introduction

Northwestern’s Biological Sciences PhD unites cell signaling, developmental genetics, ecology, and computational genomics under a single umbrella program. Students rotate through wet-labs using single-cell multi-omics to decode organoid morphogenesis, field stations tracking Great-Lakes biodiversity shifts, and data-science cores mining CRISPR screens. A professional-skills series in science policy, entrepreneurship, and inclusive pedagogy ensures graduates translate discovery into societal benefit.

💡 Suggested Project Titles

Map single-cell transcriptional trajectories during zebrafish heart regeneration

Engineer optogenetic switches controlling plant drought-response pathways

Quantify microplastic ingestion effects on freshwater invertebrate microbiomes

Develop deep-learning models predicting enhancer–promoter contacts in 3-D genome data

Characterize phage therapy efficacy against multidrug-resistant Pseudomonas in vivo

Study urban heat-island impacts on pollinator network resilience

Build a citizen-science platform crowdsourcing fungal pathogen sightings

Elucidate metabolic rewiring in tumor-associated fibroblasts via isotope tracing

Model evolutionary dynamics of antibiotic persistence using morbidostat chemostats

Reconstruct Late-Holocene vegetation shifts from sedimentary eDNA cores

Create CRISPR base-editing screens identifying synthetic-lethal cancer targets

Investigate circadian clock plasticity in Arctic ground squirrels under polar light

Design RNA aptamers sensing intracellular NAD⁺ redox states in live neurons

Assess genomic introgression in hybridizing Great-Lakes fish populations

Write a policy brief on biosafety standards for DIY gene-drive projects

Northwestern University – PhD in Biological Sciences

Advance integrative life-science research with Northwestern’s fully funded PhD.

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