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Project Ideas for Doctor of Philosophy in Neuroscience

From synapses to societies—integrative discovery of brain and behavior.

🏛 Introduction

Northwestern’s Interdisciplinary Neuroscience PhD unites cellular neurobiology, cognitive science, and computational modeling. Doctoral candidates perform two-photon imaging of dendritic plasticity, decode dream states with fMRI deep-nets, and engineer optogenetic interfaces restoring movement post-stroke. Ethics and science-communication seminars prepare graduates for academia, neurotech R&D, and policy advising.

💡 Suggested Project Titles

Map resting-state network maturation in preterm infants with graph theory

Develop closed-loop DBS algorithms for treatment-resistant depression

Quantify astrocyte calcium waves in seizure propagation using light-sheet microscopy

Model hippocampal place-cell remapping with deep reinforcement learning

Investigate gut-microbiome modulation of social behavior in germ-free mice

Create a VR navigation task probing spatial memory in Alzheimer’s patients

Engineer wireless nano-LEDs for targeted optogenetic spinal-cord stimulation

Analyze songbird vocal-learning circuits with single-cell multi-omics

Build federated brain-MRI datasets preserving privacy across hospitals

Study dopamine prediction-error signals during VR economic-game tasks

Develop EEG wearable algorithms predicting migraine onset in real time

Examine neuroimmune interactions in stress-induced depression models

Prototype haptic neurofeedback to enhance phantom-limb rehabilitation

Use Bayesian deconvolution to infer synaptic release probability from calcium traces

Write a policy white paper on ethical guidelines for consumer neurotech devices

Northwestern University – PhD in Neuroscience

Explore brain function and innovates therapies with Northwestern’s Neuroscience PhD.

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