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Project Ideas for Master of Medical Sciences in Clinical Investigation

Translate bench discoveries into evidence-based patient therapies.

🏛 Introduction

Harvard Medical School’s MMSc-CI equips physicians and scientists with rigorous training in trial design, regulatory science, and translational omics to shepherd innovations from lab to bedside. Scholars design adaptive oncology trials, mine biobank data, and earn GCP certification while crafting NIH-fundable protocols. Partnerships with MGH and Brigham accelerate graduates into PI roles and biotech clinical-development leadership.

💡 Suggested Project Titles

Phase Ib dose-escalation study of CAR-NK cell therapy

eConsent platform usability study for decentralized trials

Multi-omics biomarker discovery predicting immunotherapy response

Real-world evidence analysis of digital therapeutics adherence

Bayesian adaptive design for rare pediatric cancers

CRISPR-edited iPSC disease model informing trial endpoints

Data-safety-monitoring board simulation training toolkit

Regulatory roadmap for first-in-human gene-editing therapies

Wearable sensor validation capturing Parkinson tremor severity

Economic evaluation of companion diagnostics reimbursement

Ethics white paper on placebo use in surgical trials

Mobile app collecting PROs in heart-failure studies

Machine-learning QC pipeline for next-gen-sequencing assays

Capstone on tokenization methods for EHR-based synthetic controls

Podcast interviewing FDA reviewers on trial innovation

Interactive workshop teaching REDCap advanced features

Dashboard tracking inclusivity metrics in oncology studies

Toolkit for community-engaged recruitment in minority populations

Harvard Medical School – MMSc-CI

Lead the science that turns discoveries into lives saved.

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