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Project Ideas for Doctor of Philosophy in Biostatistics

Innovate statistical theory and computation to propel biomedical discovery.

🏛 Introduction

The Biostatistics PhD at Harvard Chan trains methodologists to craft scalable, robust inference for genomics, environmental exposures, and health-policy evaluation. Students develop novel Bayesian non-parametrics, causal-ML estimators, and privacy-preserving algorithms while collaborating with Dana-Farber trials and national cohort studies. Graduates drive analytics in academia, FDA, and tech-health giants.

💡 Suggested Project Titles

Non-parametric Bayesian model for single-cell RNA-seq trajectories

Differential privacy in federated multi-site clinical trials

Targeted-ML estimator for policy interventions on air pollution

Sparse additive hazard model for high-frequency ICU data

Surrogate-endpoint validation using hierarchical meta-analysis

Deep generative models synthesizing rare-disease cohorts

Graphical models capturing gene–environment interactions

Adaptive-sequential design for platform oncology trials

Open-source R package for doubly robust survival estimators

Ethics memo on fairness in predictive-risk scores for sepsis

Visualization dashboard of uncertainty in climate-health projections

Workshop on reproducible research workflows with Quarto and GitHub

Harvard – PhD in Biostatistics

Build the statistical engines powering precision health.

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