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Project Ideas for Doctor of Philosophy in Immunology

Decode immune networks to combat disease and advance precision medicine.

🏛 Introduction

Harvard’s Immunology PhD unites HMS labs and Harvard-affiliated hospitals to probe innate sensors, engineer CAR-T cells, and profile single-cell immune atlases. Trainees translate bench insights into vaccines and checkpoint inhibitors, publishing in *Nature* while mentoring youth through Science Club for Girls.

💡 Suggested Project Titles

CRISPR screen mapping viral-restriction factors in macrophages

Neoantigen prediction pipeline for personalized cancer vaccines

Spatial transcriptomics of T-cell niches in tuberculosis lesions

Hydrogel-delivered mRNA vaccine enhancing mucosal immunity

Thesis chapter on trained-immunity epigenetic reprogramming

Machine-learning model forecasting cytokine storm risk

Organoid co-culture to study gut microbiota–immune crosstalk

Nanobody library targeting intracellular oncogenic proteins

Ethics paper on equitable access to cell-based therapies

Open-source dashboard visualizing global vaccine hesitancy

In vivo imaging of B-cell germinal-center dynamics

Policy brief on pandemic-preparedness immune correlates

Workshop on flow cytometry panel design for resource-limited labs

Citizen-science app crowdsourcing allergy symptom mapping

Podcast interviewing pioneers of innate-like T-cell discovery

Interactive VR lab tour explaining antigen presentation

Harvard – PhD in Immunology

Harness immune insight to protect global health.

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