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Project Ideas for Master of Science in Biochemistry and Biophysics

Interrogate life’s molecular machinery with cutting-edge techniques.

🏛 Introduction

UNC’s MS in Biochemistry & Biophysics trains scientists to visualize proteins at atomic resolution, map metabolic networks, and design therapeutics. Students operate cryo-EM and NMR spectrometers, program molecular-dynamics simulations on the BioComp cluster, and engineer CRISPR screens in the Lineberger Comprehensive Cancer Center. Professional-development seminars cover tech transfer and biotech entrepreneurship.

💡 Suggested Project Titles

Cryo-EM structure of SARS-CoV-2 accessory proteins

All-atom MD simulation exploring antibiotic efflux pumps

High-throughput screen identifying inhibitors of oncogenic kinases

Metabolomics profiling of cancer-cell metabolic rewiring

Optogenetic control of enzyme kinetics in live cells

White paper on open-data standards for structural biology

Protein-engineering library targeting plastic-degrading enzymes

Podcast explaining phosphorylation signaling to the public

Grant proposal for time-resolved XFEL experiments

AI-based prediction of protein-protein interaction hotspots

Infographic visualizing ATP synthase rotary mechanism

Fluorescence-lifetime imaging of NADH in neurodegeneration models

Workshop on Bayesian statistics for enzyme-kinetics analysis

VR molecular visualization teaching secondary-structure motifs

Policy brief on CRISPR patent landscapes and access

Manuscript on hydrogen-deuterium exchange mass-spec workflows

Community outreach demo using 3-D printed protein models

UNC-Chapel Hill – MS in Biochemistry & Biophysics

Decode and engineer biomolecules to advance medicine and biotechnology.

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