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Project Ideas for Master of Science in Pathology

Bridge molecular diagnostics and translational discovery in disease.

🏛 Introduction

UNC’s MS in Pathology places students at the interface of clinic and bench. Trainees validate AI histopathology pipelines, culture patient-derived organoids, and mine proteogenomic datasets to uncover therapeutic targets. Rotations in Surgical Pathology and Molecular Oncology accelerate translational impact.

💡 Suggested Project Titles

Deep-learning model classifying skin-lesion whole-slide images

Organoid drug-screen predicting chemo response in pancreatic cancer

Spatial transcriptomics map of immune infiltrates in triple-negative breast cancer

Policy brief on digital-path slide-sharing interoperability

Proteomics workflow identifying biomarkers for sepsis prognosis

CRISPR screen mapping synthetic lethality in KRAS-mutant lines

Grant proposal for low-cost HPV genotyping in LMIC cytology labs

White paper on ethical use of patient tissue for AI training

Infographic explaining PD-L1 scoring harmonization

Liquid-biopsy assay detecting EGFR exosome RNA

VR training module for residents on lymphoma pattern recognition

Evaluation of fixative alternatives preserving RNA quality

Meta-analysis of TMB as pan-cancer predictive biomarker

Dashboard tracking turnaround times in intraoperative consults

Citizen pathology initiative annotating benign histology tiles

Automated QC pipeline for IHC stain intensity

Podcast discussing pathology-lab decarbonization strategies

Lean study reducing specimen ID errors

Workshop on gender disparities in academic pathology leadership

Comparative study of multiplex IF vs CyTOF imaging costs

UNC-Chapel Hill – MS in Pathology

Advance precision diagnostics through molecular and digital pathology.

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