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Project Ideas for Master of Science in Genetics and Molecular Biology

Decode genomes to advance precision medicine and evolutionary insight.

🏛 Introduction

UNC’s MS in Genetics & Molecular Biology trains scientists to perform CRISPR base-editing, single-cell multi-omics, and phylogenomic inference. Students sequence ancient DNA in ISO-class clean rooms, use PacBio long reads to resolve structural variants, and visualize chromatin loops with Hi-C. Ethical genomics seminars tackle data sovereignty and clinical translation.

💡 Suggested Project Titles

Base-edit screen correcting CFTR mutations in airway organoids

Pan-genome assembly of drought-tolerant maize landraces

Long-read detection of tandem repeats in neurodegenerative loci

Phylogenomic tree of antibiotic-resistance island evolution

Policy brief on equitable newborn genome screening programs

Synthetic gene drive containment assay in Drosophila

Hi-C mapping of enhancer hijacking in pediatric sarcomas

Metagenomic survey of gut virome in vegan diets

Federated learning model predicting rare-variant pathogenicity

Interactive dashboard exploring GWAS hits across ancestries

Grant proposal for Indigenous community led biobank governance

Podcast demystifying CRISPR gene therapy trials

VR chromosome tour illustrating epigenetic landscapes

Workshop on FAIR principles for variant annotation datasets

White paper on gene-editing ethics in conservation biology

UNC-Chapel Hill – MS in Genetics & Molecular Biology

Merge molecular innovation and ethical vision to transform genomics.

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