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Project Ideas for Master of Science in Bioinformatics and Computational Biology

Drive discoveries at the intersection of life science and AI.

🏛 Introduction

UNC’s MS in Bioinformatics & Computational Biology instructs students to wrangle petabyte-scale omics data, build graph neural-networks for drug discovery, and visualize single-cell atlases. Coursework integrates cloud-native workflows, ethics of genomic privacy, and entrepreneurial bootcamps with the KickStart Venture Fund. Practicum teams partner with UNC Lineberger, RTI International, and emerging biotech startups.

💡 Suggested Project Titles

Snakemake workflow automating scRNA-seq analysis on AWS

Graph-neural network predicting protein–ligand affinity

Pangenome assembly of antibiotic-resistant bacterial strains

Privacy-preserving federated learning for clinical genomics

Dashboard visualizing epigenomic changes during cell reprogramming

Policy memo on equitable genomic data sharing with tribal nations

Variant-calling pipeline benchmark across cloud platforms

Podcast explaining CRISPR base-editing ethics

Metagenomic study of urban microbiomes on public transit

Machine-learning model annotating non-coding regulatory regions

Grant proposal for AI drug repurposing against neglected diseases

Interactive network map of host–virus protein interactions

White paper on standardizing metadata in multi-omics consortia

Hackathon toolkit for visualizing long-read transcriptomics

Infographic comparing compression algorithms for FASTQ files

Workshop on containerization best practices in bioinformatics

UNC-Chapel Hill – MS in Bioinformatics & Computational Biology

Harness computation to translate big-data biology into health breakthroughs.

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