Duke’s PhD in Cell Biology propels scholars into live-cell microscopy, quantitative proteomics, and optogenetic circuit-mapping to reveal how sub-cellular machines orchestrate development, immunity, and disease. First-year rotations span lattice light-sheet imaging of endosomal trafficking, single-particle cryo-ET of nuclear-pore transport, and CRISPR screens for ferroptosis defense pathways. Professional-skills studios teach grant writing, biotech entrepreneurship, and K-12 outreach, while the program’s open-science charter mandates preregistered protocols and citable data sets. Graduates emerge as rigorously trained, policy-savvy investigators ready for academic, pharma, or science-communication leadership.
Optogenetic control of lysosome–ER contact sites in calcium signaling
Single-molecule FRET mapping of chaperone–client interactions
Cryo-ET atlas of Golgi ribbon remodeling during mitosis
AI-augmented segmentation pipeline for lattice light-sheet volumes
Synthetic lipid droplet bioreactors for in-cell metabolic engineering
Proximity-labeling proteomics of stress-granule cores
Mathematical model of kinetochore force adaptation
CRISPRi screen for genes suppressing oncogenic micronuclei
Photon-counting FLIM to quantify NAD⁺/NADH redox in live neurons
Nano-needle electroporation delivering base-editing complexes
VR outreach module visualizing cytokinesis in 4-D
Public-policy brief on gene-drive governance in vector control
Blockchain ledger tracking antibody lot provenance in labs
Citizen-science microscope kit for high-school cell imaging
Open-access database of mutant organelle morphologies
Decode and engineer the cell’s inner universe through Duke’s Cell Biology doctorate.
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