Duke’s Biophysics BS merges rigorous physics, chemistry, and computational modeling to reveal how biomolecules and cells obey—and sometimes exploit—physical laws. Students gain fluency in statistical mechanics, quantum biology, and single-molecule instrumentation. Research rotations pair undergraduates with faculty using cryo-EM to resolve protein complexes at near-atomic resolution and optical tweezers to measure DNA mechanics. A distinctive theoretical track emphasizes differential-equation modeling of biological networks, preparing graduates for graduate programs or biotech R&D.
Molecular dynamics simulation of SARS-CoV-2 spike conformational changes
Optical-tweezer assay quantifying chromatin fiber elasticity
Cryo-EM reconstruction pipeline for ion-channel gating states
Fluorescence correlation spectroscopy of protein phase separation
Computational model of actin polymerization during cell motility
Coarse-grained simulation of lipid rafts in neuronal membranes
Isotope-labeled NMR study of intrinsically disordered proteins
Machine-learning classification of single-particle cryo-EM images
Laser-trap investigation of motor-protein stepping kinetics
Monte-Carlo modeling of cooperative ligand binding
Photonic crystal biosensor detecting enzymatic conformational shifts
Brownian dynamics visualization tool for educational outreach
AI-driven design of protein-based biomaterials
Quantum-mechanical study of proton tunneling in enzyme catalysis
GPU-accelerated algorithm for smFRET trajectory analysis
AFM mapping of bacterial cell-wall stiffness under antibiotics
Optogenetic control of intracellular phase-transition processes
Spatial statistics of virus capsid assembly pathways
Bio-inspired metamaterials based on spider-silk elasticity
Public science exhibit illustrating thermodynamics of life
Decode the physical forces that govern living systems in Duke’s Biophysics major.
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