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Project Ideas for Doctor of Philosophy in Neurobiology

Circuit dynamics and neural engineering across scales of cognition.

🏛 Introduction

Duke’s Neurobiology Ph.D. melds two-photon imaging, connectomics, and computational modeling to unveil how brains compute. Candidates decode ensemble dynamics during social decision-making, build wireless optogenetic implants, and craft closed-loop BCIs restoring motor intent. Translational rotations pair labs with Duke Hospital neurosurgeons for real-world impact.

💡 Suggested Project Titles

Deep-learning reconstruction of speech from cortical activity

Whole-brain light-sheet mapping of stress circuitry in zebrafish

Graph analysis of synaptic connectomes in autism models

Wireless µLED optogenetics for freely moving primates

NMDA-receptor CRISPR editing reversing cognitive deficits

Citizen-science EEG study on sleep and problem-solving

VR navigation task probing entorhinal grid remapping

Closed-loop stimulation for chronic pain modulation

Policy memo on consumer neuro-wearable data privacy

Open-source toolbox for calcium-imaging spike inference

Stem-cell-derived cortical organoid electrophysiology atlas

Public science art show visualizing brainwave music

Duke University – PhD in Neurobiology

Decode mind and engineer therapeutics through Duke’s Neurobiology Ph.D.

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