Duke’s Ph.D. in Molecular Cancer Biology arms researchers with CRISPR, single-cell spatial-omics, and AI drug-design to disarm oncogenic networks. Students map tumor–immune co-evolution, visualize chromatin remodeling in live nuclei, and screen covalent inhibitor libraries on high-throughput robotics. Partnerships with Duke Cancer Institute translate bench hits into Phase I trials, while policy seminars interrogate access and affordability.
PROTAC degradation of mutant KRAS G12D
Spatial-omics atlas of immune-excluded pancreatic tumors
Machine-learning prediction of synthetic-lethal gene pairs
Live-cell imaging of PARP-inhibitor DNA repair dynamics
Neoantigen vaccine design using deep-mutational scanning
CRISPR loss-of-function screen for ferroptosis suppressors
Nanobody library targeting MYC transcriptional complexes
Mathematical model of clonal resistance under adaptive therapy
Organoid-on-chip assay for tumor-stromal metabolic crosstalk
Blockchain provenance for patient-derived xenograft tissue
VR outreach exhibit on hallmarks of cancer
Policy memo on AI companion diagnostics regulation
Citizen-science app reporting environmental carcinogen hotspots
Open-source pipeline for oncogenic fusion-gene detection
CAR-macrophage engineering targeting solid-tumor stroma
Decode and defeat cancer’s circuitry with Duke’s cutting-edge doctorate.
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