Duke’s Pharmacology Ph.D. leverages structural biology, chem-proteomics, and systems pharmacology to craft safer, smarter drugs. Trainees solve GPCR crystal structures, deploy high-content phenotypic screens, and model polypharmacy effects with AI. Entrepreneur-in-residence mentors steer spinouts from hit to IND.
Allosteric modulator discovery for cannabinoid CB2 receptor
Chem-proteomic profiling of covalent kinase inhibitors
Physiologically based PK model optimizing nanoparticle delivery
AI de-novo design of BBB-permeable peptides
Organoid-based cardiotoxicity phenotypic screen
Blockchain smart contracts for compound IP licensing
Citizen-science QSAR game crowdsourcing descriptor ideas
Policy memo on accelerated approval surrogate endpoints
Cryo-EM of sodium-channel drug-binding conformers
Deep-learning prediction of drug-drug interaction risk
Public outreach animation on pharmacogenomics
Invent therapeutics that change lives with Duke’s Pharmacology doctorate.
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