Ohio State’s MS in Biochemistry focuses on the chemical processes that underlie life and disease. With access to modern research facilities, students conduct original investigations into enzymology, protein dynamics, cell signaling, metabolism, and molecular genetics. The program bridges the gap between biology and chemistry, providing strong preparation for PhD programs, biotechnology careers, and biomedical research roles.
Elucidating the mechanism of allosteric regulation in metabolic enzymes
Structural characterization of disease-related proteins using cryo-EM
Assessing the role of oxidative stress in neurodegenerative disease progression
Engineering enzyme variants for industrial biocatalysis under extreme pH
Developing biosensors for real-time detection of glucose or lactate in biofluids
Mapping protein–protein interactions in the apoptosis signaling pathway
Designing targeted inhibitors for viral proteases using structure-guided drug design
Analyzing the lipid composition of cancer cell membranes under metabolic stress
Exploring post-translational modifications in histones during cell cycle phases
Studying the kinetics of DNA polymerase fidelity in replication forks
Evaluating CRISPR–Cas protein stability under intracellular conditions
Using site-directed mutagenesis to investigate active site residues in peptidases
Modeling mitochondrial dysfunction in Type II diabetes using cell culture assays
NMR-based analysis of protein folding intermediates in chaperone-assisted folding
Exploring the biochemical role of selenoproteins in antioxidant defense
Designing RNA-based therapeutics for genetic diseases with known splice defects
Investigating the role of iron–sulfur clusters in bacterial electron transport chains
Studying metabolomic shifts during stem cell differentiation into neural lineages
Developing ELISA assays for novel cytokines linked to inflammatory bowel disease
Expression and purification of recombinant enzymes for drug screening applications
Unlock life’s chemistry and pursue biomedical innovation with OSU’s Biochemistry MS.
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