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Project Ideas for Doctor of Philosophy in Neuroscience

A brain-focused PhD exploring the molecular, cognitive, and computational bases of behavior and disease.

🏛 Introduction

Ohio State’s PhD in Neuroscience provides interdisciplinary research training in neural development, behavior, neuroimmunology, computational neuroscience, and neurodegenerative disease. Students use tools ranging from electrophysiology and imaging to genetic engineering and AI modeling. With strong NIH funding and clinical partnerships, graduates lead academic and translational neuroscience efforts worldwide.

💡 Suggested Project Titles

Optogenetic control of hippocampal circuits during memory retrieval tasks

Longitudinal study of white matter changes in adolescents with early-onset depression

Modeling Alzheimer’s disease progression using induced pluripotent stem cells

Analyzing gut microbiota impact on brain development using germ-free mouse models

EEG signal decoding during decision-making in high-stakes tasks

Synaptic plasticity mapping in cortical neurons using two-photon microscopy

AI-based detection of early biomarkers for multiple sclerosis relapse

Single-cell RNA sequencing of spinal cord tissues after injury

Investigating dopaminergic neuron degeneration in Parkinson’s mouse models

Studying gender differences in chronic stress effects on amygdala structure

Computational modeling of large-scale brain networks in epilepsy prediction

Sleep disruption analysis in veterans with PTSD using polysomnography

Development of closed-loop deep brain stimulation systems with adaptive feedback

Evaluating neurovascular coupling in fMRI across cognitive aging populations

CRISPR-based gene knockdown of glial factors regulating neuroinflammation

Studying oxytocin’s role in social bonding in autism mouse models

Designing BCI interfaces for patients with locked-in syndrome

Machine learning classifiers for seizure detection in continuous EEG streams

Testing novel neuroprotective agents in stroke injury models

Correlating environmental toxin exposure with cortical development anomalies

Ohio State – PhD in Neuroscience

Explore brain–behavior relationships and neurological discovery with OSU’s Neuroscience PhD.

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