The PhD in Biochemistry and Molecular Biology at UF focuses on elucidating the molecular underpinnings of life. Students conduct original research in enzymology, structural biology, gene regulation, cellular signaling, and disease pathways. With access to state-of-the-art labs and interdisciplinary faculty, graduates are prepared for careers in academia, biotech, pharma, or translational research.
Thesis on protein-protein interactions regulating apoptosis in cancer cells
Structural characterization of ribosome-associated chaperones during protein folding
CRISPR-mediated enhancer knockout study on transcriptional regulation in stem cells
Molecular dynamics simulation of DNA repair enzymes under oxidative stress
Enzymatic mechanism elucidation for metabolic bottleneck reactions in glycolysis
Single-molecule fluorescence tracking of RNA polymerase binding events
Investigation of post-translational modifications in Alzheimer’s disease models
RNA interference study on mRNA stability regulators in inflammation
X-ray crystallography of allosteric sites in bacterial resistance enzymes
Study on metabolic reprogramming of immune cells in tumor microenvironments
Gene expression profiling of neurodegenerative disease markers in mouse models
Thesis on mitochondrial-nuclear genome communication and energy homeostasis
High-throughput screening for small molecule inhibitors of DNA helicases
Structural modeling and docking of peptide inhibitors for protease targets
Comparative proteomics analysis in aging vs. young murine skeletal muscle
Epigenetic control of transcription factors in muscle differentiation
Mechanistic dissection of ubiquitin-proteasome pathways in protein turnover
Design and validation of riboswitch-controlled gene expression systems
Study of non-coding RNAs in embryonic development and lineage specification
Functional analysis of rare genetic variants in familial cardiovascular disease
Uncover molecular mechanisms behind health and disease through original scientific discovery.
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