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Project Ideas for Doctor of Philosophy in Microbiology and Cell Science

Uncover molecular interactions and cellular mechanisms to drive life sciences innovation.

🏛 Introduction

UF’s PhD in Microbiology and Cell Science trains students in advanced topics including host-pathogen interactions, microbial genetics, cell signaling, and metabolic regulation. Students conduct cutting-edge research using CRISPR, microscopy, omics technologies, and synthetic biology. The program supports publication-focused, grant-funded inquiry and prepares graduates for careers in biotech, academia, and government labs.

💡 Suggested Project Titles

Characterization of CRISPR-Cas systems in novel extremophilic microorganisms

Study on metabolic reprogramming in bacterial biofilm communities

Thesis on host epithelial response to commensal vs. pathogenic E. coli

Analysis of cell cycle checkpoint regulation in DNA-damaged mammalian cells

Fluorescence imaging of intracellular pathogen replication dynamics

Development of biosensors for quorum sensing molecule detection

Gene expression profiling of antibiotic-tolerant persister cells in tuberculosis

Study on post-translational modifications regulating autophagy in yeast models

Investigation of microbiota-derived metabolites in colorectal cancer progression

Development of synthetic microbial consortia for waste bioremediation

Comparative study of cytoskeletal remodeling during viral egress

Phage therapy modeling and optimization for multidrug-resistant bacterial infections

Mitochondrial calcium signaling study in cell stress responses

Pathogen effector protein discovery using comparative proteomics

Analysis of immune evasion mechanisms in intracellular protozoan parasites

Thesis on lysosomal dysfunction in neurodegenerative disease models

Design of RNA interference tools to silence bacterial virulence factors

Spatial transcriptomics study of inflammation sites in infected tissues

Synthetic biology approach to engineer probiotic strains for drug delivery

Investigation of microbial symbiosis in hydrothermal vent ecosystems

University of Florida – PhD in Microbiology and Cell Science

Advance cellular and microbial understanding to power breakthroughs in science and medicine.

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