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Project Ideas for Doctor of Philosophy in Genetics and Genomics

Explore the foundations of inheritance and evolution through molecular and computational research.

🏛 Introduction

UF’s PhD in Genetics and Genomics offers a rigorous training platform in genome sequencing, molecular genetics, bioinformatics, and functional genomics. Students conduct original research that informs agriculture, medicine, evolution, and biotechnology. The program encourages interdisciplinary work and prepares graduates for high-level research in academia, healthcare, or private industry.

💡 Suggested Project Titles

Functional annotation of non-coding variants in congenital heart disease cohorts

CRISPR-Cas9-mediated gene editing for functional genomics in zebrafish embryos

Genome-wide association study of drought tolerance in Florida citrus crops

Comparative genomics of microbial consortia in coral reef microbiomes

Single-cell RNA sequencing of neural crest cell differentiation trajectories

Study of transgenerational epigenetic inheritance in mammalian development

Thesis on genome evolution in invasive plant species using long-read sequencing

Methylation landscape comparison between tumor and adjacent normal tissue

Population genomics of endangered species using ancient DNA samples

Thesis on host-microbiome co-evolution using metagenomic and transcriptomic data

Design of machine learning models to predict enhancer-promoter interactions

Long-read assembly and annotation of under-characterized plant genomes

Study on viral integration sites and oncogene activation in HPV-positive cancers

Analysis of horizontal gene transfer events in soil microbiota

Bioinformatics pipeline development for high-throughput variant calling

Genomic imprinting and parent-of-origin effects in placental mammals

Synthetic biology approach to create tunable gene circuits in bacteria

Thesis on copy number variation detection in neurodevelopmental disorders

Genome editing of metabolic pathways in yeast for industrial bioproduction

RNA interference study of immune regulators in invertebrate model organisms

University of Florida – PhD in Genetics and Genomics

Shape the future of biology and biotechnology through genome-focused doctoral research.

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