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Project Ideas for Master of Science in Medicine

Bench-to-bedside MSMed linking translational omics, AI trials & regulatory strategy.

🏛 Introduction

Designed for scientists bridging lab and clinic, USC’s MS in Medicine immerses students in single-cell transcriptomics, adaptive clinical-trial design and FDA fast-track pathways. Learners analyze CRISPR screens with Seurat, build Bayesian dose-escalation models, and craft digital-therapeutic IND packets. Rotations at Keck Medicine connect bench protocols to patient consents, while an Ethics core unpacks AI biomarker biases. Graduates orchestrate pipelines turning omics insights into approved interventions.

💡 Suggested Project Titles

Digital biomarker validation for smartwatch AFib detection

Bayesian adaptive platform trial simulator in R Shiny

CRISPR pooled screen identifying chemo-sensitizer genes

Real-world evidence analytics on EHR oncology cohorts

Policy brief on AI companion diagnostics under CLIA

Synthetic control arm construction from historical trials

Voice-analysis classifier for early Parkinson’s detection

Standard-operating procedure for decentralized consent e-sign

Nanopore sequencing pipeline for rapid sepsis pathogen ID

Blockchain-based chain-of-custody for bio-specimen labs

AI-generated lay summaries improving trial recruitment

Pharmacoeconomic model of gene therapy cost offsets

Virtual twin of tumor micro-environment for in-silico trials

Omics-driven repurposing of shelved pharma compounds

Digital Pathology CNN comparing H&E vs. multiplex IHC

USC – MS in Medicine

Translate molecular discoveries into clinically approved breakthroughs.

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